FDA to allow ‘mix-and-match’ approach on coronavirus booster vaccines

The Food and Drug Administration is expected to say this week that people can get coronavirus vaccine booster shots that are different from their initial doses, according to two federal officials familiar with the situation.

The agency is rushing to make the announcement Wednesday as part of its authorization of boosters for the Moderna and Johnson & Johnson vaccines. The FDA may also say that people should generally stick to the same vaccine if possible, according to the two federal officials, who spoke on the condition of anonymity because they were not authorized to discuss the issue.